In vivo Data


OCT-post OCT-3M 



Effective scaffolding followed by programmed dismantling at around 3 months to enable positive remodeling and safe complete resorption within 24 months


Key facts :

  • Prevent acute and chronic recoil
  • Transient and effective scaffolding
  • Allow the artery to remodel after the scaffold dismantles
  • Black boxes turning white is driven by the polymer hydration, essential for hydrolysis


Publications :

Lafont et al, Restenosis after experimental angioplasty. Intimal, medial, and Adventitial changes associated with constrictive remodeling. Circ Res. 1995 Jun;76(6):996-1002

Lafont A et al, Endothelial dysfunction and collagen accumulation: two independent factors for restenosis and constrictive remodeling after experimental angioplasty. Circulation. 1999 Sep 7;100(10):1109-15

Virmani R et al, Drug eluting stents: are human and animal studies comparable? Heart. 2003 Feb;89(2):133-8. Review.

Durand, et al, Head-to-head comparison of a drug-free early programmed dismantling polylactic acid bioresorbable scaffold and a metallic stent in the porcine coronary artery: six-month angiography and optical coherence tomographic follow-up study. Circ Cardiovasc Interv. 2014 Feb;7(1):70-9